第 1259 回 Immune responses Against HIV, Dengue and Zika演者： David Ian Watkins, PhD (Professor, Pathology, University of Miami Medical School )
場所： 京都大学ウイルス再生研２号館（旧ウイルス研本館）１階 セミナー室
My laboratory focuses on describing the immune responses to important human pathogens with the long term goal of designing vaccines, treatments and diagnostics for these viruses. I will first describe recent results from attempts to find a vaccine for HIV using the non-human model of SIV infection. I will also present results from collaboration between Dr. Esper Kallas's laboratory at the University of Sao Paulo, Brazil and my laboratory in Miami. We have cloned, expressed and determined binding and neutralization of approximately 300 monoclonal antibodies isolated from plasmablasts after either vaccination with the NIH Dengue vaccine or Zika virus infection. I will discuss recent attempts at using one of these antibodies to block Dengue infection. I will also describe new antibodies against Zika that might be useful for diagnostics.
連絡先：システムウイルス学分野 小柳 義夫 (TEL:751−4811, e-mail：firstname.lastname@example.org）